A STATISTICALLY SELF-CONSISTENT FATIGUE DAMAGE ACCUMULATION MODEL INCLUDING LOAD SEQUENCE EFFECTS UNDER SPECTRUM LOADING

A statistically self-consistent fatigue damage accumulation model including load sequence effects under spectrum loading

A probabilistic methodology is proposed to evaluate fatigue damage accumulation and fatigue lives of specimens under variable amplitude loading.With probabilistic modifications in the present model, the calculative consistency is achieved between fatigue damage and fatigue life.The load sequence effects on fatigue damage accumulation are properly a

read more


Chronopharmacology of immune-related diseases

Clock genes, circadian pacemaker resides in the paired suprachiasmatic nuclei (SCN), control various circadian rhythms in many biological processes such as physiology and behavior.Clock gene regulates many diseases such as cancer, immunological dysfunction, metabolic syndrome and sleep disorders etc.Chronotherapy is especially relevant, when the ri

read more


Thoracoscopic-assisted surgical stabilisation with a locking compression plate for pectus excavatum in a Maine Coon kitten

Case summary A 4-month-old Maine Coon kitten was presented for the surgical correction of pectus excavatum (PE).Originally presenting with progressive respiratory distress, the cat underwent video-assisted thoracoscopic surgery (VATS) for stabilisation using a locking compression plate.Postoperative complications Jars included two separate episodes

read more